Hammer GE, Gonzalez F, Champsaur M, Cado D, Shastri N. ![]() ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. Kanaseki T, Blanchard N, Hammer GE, Gonzalez F, Shastri N. In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Hammer GE, Gonzalez F, James E, Nolla H, Shastri N. The final touches make perfect the peptide-MHC class I repertoire. Construction and destruction of MHC class I in the peptide-loading complex. Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, DeFranco A, Criswell LA, Nakamura MC, Ma A. Molecular control of steady-state dendritic cell maturation and immune homeostasis. Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. PMID 25609235 DOI: 10.1038/Ncomms6779Ĭallahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Kanayama M, Inoue M, Danzaki K, Hammer G, He YW, Shinohara ML. Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. Liang J, Huang HI, Benzatti FP, Karlsson AB, Zhang JJ, Youssef N, Ma A, Hale LP, Hammer GE. Abstract 019: A20 in Dendritic Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T Cell Activation Hypertension. Lu X, Rudemiller N, Zhang J, Privratsky J, Hammer G, Zhang J, Wen Y, Ren J, Crowley SD. A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T Cell Activation. Lu X, Rudemiller NP, Wen Y, Ren J, Hammer G, Griffiths R, Privratsky JR, Yang B, Sparks MA, Crowley SD. C-C Motif Chemokine Receptor 7 Exacerbates Hypertension Through Effects on T Lymphocyte Trafficking. Wen Y, Rudemiller NP, Zhang J, Lu X, Ren J, Privratsky JR, Griffiths R, Zhang JJ, Hammer GE, Crowley SD. The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection. Liang J, Zhang JJ, Huang HI, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, Hammer GE.
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